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L-arginine biosynthesis II (acetyl cycle)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
L-aspartate + L-citrulline + ATP <=> H+ + argininosuccinate + diphosphate + AMP 6.3.4.5 argininosuccinate synthase
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N2-Acetyl-L-ornithine + 2-oxoglutarate <=> L-glutamate + N-acetyl-L-glutamate_5-semialdehyde 2.6.1.11 acetylornithine transaminase
2.6.1.13 ornithine aminotransferase
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L-ornithine + Carbamoyl_phosphate <=> H+ + L-citrulline + phosphate 2.1.3.3 ornithine carbamoyltransferase
2.1.3.6 putrescine carbamoyltransferase
3.5.3.12 agmatine deiminase
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–
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N-acetyl-L-glutamate_5-semialdehyde + NADP+ + phosphate <=> H+ + N-acetyl-L-glutamyl_5-phosphate + NADPH 1.2.1.38 N-acetyl-gamma-glutamyl-phosphate reductase
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argininosuccinate <=> L-arginine + fumarate 4.3.2.1 argininosuccinate lyase
4.3.2.2 adenylosuccinate lyase
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ATP + L-glutamine + HCO3- + H2O <=> L-glutamate + Carbamoyl_phosphate + ADP + phosphate + H+ 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
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N-acetyl-L-glutamate + ATP <=> N-acetyl-L-glutamyl_5-phosphate + ADP 2.7.2.8 acetylglutamate kinase
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L-glutamate + acetyl-CoA <=> H+ + N-acetyl-L-glutamate + CoA 2.3.1.1 amino-acid N-acetyltransferase
2.3.1.17 aspartate N-acetyltransferase
2.3.1.183 phosphinothricin acetyltransferase
2.7.2.8 acetylglutamate kinase
6.3.4.16 carbamoyl-phosphate synthase (ammonia)
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–
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L-glutamate + N2-Acetyl-L-ornithine <=> N-acetyl-L-glutamate + L-ornithine 2.3.1.35 glutamate N-acetyltransferase
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